DIMYRISTOYL PHOSPHATIDYLCHOLINE

Dimyristoylphosphatidylcholine（DMPC） is a phosphatidylcholine, a kind of phospholipid. As a phospholipid, DMPC can form a micelle with a hydrophobic core to contain lipophilic drugs while maintaining a hydrophilic outer portion to allow increased solubility of the drug in the aqueous environment of the blood or gastrointestinal tract. It can also be used to prepare liposomes and lipid nanoparticles(LNPs). DMPC is a frequently studied artificial lipid because it undergoes a phase transition at a convenient temperature. Upon cooling below 23.6℃ it undergoes a transition from the liquid crystalline phase to the solid rippled phase, characterized by periodic corrugations of the bilayer.

DIMYRISTOYLPHOSPHATIDYLCHOLINE (DMPC) SPECIFICATIONS

ADVANTAGES AND APPLICATIONS OF DIMYRISTOYL PHOSPHATIDYLCHOLINE

CDE/DMF registration; in stock; High purity

Dimyristoylphosphatidylcholine (DMPC) in combination with cholesterol is used as biomembrane model. Dimyristoylphosphatidylcholine (DMPC) has been used in the preparation of some special liposomes.

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