China Medicina
Medicina

Diethyl malonate

Diethyl malonate is the diethyl ester of malonic acid. It naturally occuring in grapes and strawberries, is widely used in the manufacture of pharmaceuticals, antioxidants, and dyes.

Diethyl malonate is used in organic synthesis for the preparation of alpha-aryl malonates, mono-substituted and di-substituted acetic acid, barbiturates and artificial flavorings. It is also involved in the synthesis of pharmaceuticals like chloroquine, butazolidin and barbital. It acts as intermediate in the synthesis of vitamin B1, vitamin B6, non-steroidal anti-inflammatory agents agrochemicals and perfumes. In Knoevenagel condensation reaction, it reacts with benzaldehyde to get diethyl benzylidenemalonate.

Brand: Soarwin

CAS No.: 105-53-3

EC number: 203-305-9

Molecular Formula: C7H12O4

Density: 1.055 g/mL at 25 °C (lit.)

Boiling point: 199 °C (lit.)

Melting point: -51--50 °C (lit.)

Flashing point: 212°F

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Diethyl malonate

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